Recent advances in proteomic analysis to study carotid artery plaques.

ABSTRACT:

Objective

We sought to identify differentially expressed proteins in serum, plasma, and plaque samples of patients with carotid atherosclerotic lesions.

Methods

We performed a systematic review of the proteomic profile of serum, plasma, and plaque samples of patients with carotid artery disease. We included full-length peer-reviewed studies of adult humans and reported them using PRISMA guidelines. The quality of the design and content of the articles included in the review was assessed using the Newcastle-Ottawa scale.

Results

We included six peer-reviewed articles reporting protein expression in serum, plasma, or plaque samples from patients with carotid atherosclerosis. Three were single-center cross-sectional studies, two were single-center case-control studies, a

SUBMITTER: Cruz-Gonzalez G 

PROVIDER: S-EPMC11440263 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature