Real-world use of inhaled corticosteroid/formoterol as needed in adults with mild asthma: the PRIME study.

ABSTRACT:

Introduction

Inhaled corticosteroid/formoterol fumarate (ICS/FF) as needed is recommended by the Global Initiative for Asthma (GINA) as sole therapy in adults with mild asthma, with low-dose maintenance ICS plus short-acting β₂-agonist (SABA) as an alternative. SABA alone is no longer recommended. Given these changes in recommendations, the observational PRIME study aimed to describe real-world treatment patterns in mild asthma in Europe.

Methods

Adults with asthma receiving low-dose maintenance ICS, or as needed ICS/FF or SABA were followed for 6 months. Data collected included Asthma Control Test (ACT), Asthma Control Questionnaire 5-item (ACQ-5), forced expiratory volume in 1 s (FEV₁) and asthma exacerbations.

Results

The study was conducted i

SUBMITTER: Brusselle G 

PROVIDER: S-EPMC11440373 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature