Tether-entangled conjugated helices.

ABSTRACT: A new design concept, tether-entangled conjugated helices (TECHs), is introduced for helical polyaromatic molecules. TECHs consist of a linear polyaromatic ladder backbone and periodically entangling tethers with the same planar chirality. By limiting the length of tether, all tethers synchronously bend and twist the backbone with the same manner, and change it into a helical ribbon with a determinate helical chirality. The 3D helical features are customizable via modular synthesis by using two types of synthons, the planar chiral tethering unit (C ₂ symmetry) and the docking unit (C _2h symmetry), and no post chiral resolution is needed. Moreover, TECHs possess persistent chiral properties due to the covalent locking of helical configuration by te

SUBMITTER: Jin K 

PROVIDER: S-EPMC11440437 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature