The influence of growth rate-controlling feeding strategy on the surfactin production in Bacillus subtilis bioreactor processes.

ABSTRACT:

Background

The production of surfactin, an extracellular accumulating lipopeptide produced by various Bacillus species, is a well-known representative of microbial biosurfactant. However, only limited information is available on the correlation between the growth rate of the production strain, such as B. subtilis BMV9, and surfactin production. To understand the correlation between biomass formation over time and surfactin production, the availability of glucose as carbon source was considered as main point. In fed-batch bioreactor processes, the B. subtilis BMV9 was used, a strain well-suited for high cell density fermentation. By adjusting the exponential feeding rates, the growth rate of the surfactin-producing strain, was controlled.

Results

Using different growth rates

SUBMITTER: Hiller E 

PROVIDER: S-EPMC11440882 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature