Postnatal weight loss and neurodevelopmental outcomes at age 3 years in extremely preterm infants: a cohort study.

ABSTRACT:

Background

Previous research has suggested a correlation between postnatal maximum weight loss (MWL) and both neonatal mortality and morbidities in extremely preterm infants. However, the relationship between MWL and neurodevelopmental outcomes remains underexplored.

Methods

In a single-center, retrospective cohort study at Okayama Medical Center, we evaluated data from extremely preterm infants admitted to the neonatal intensive care unit from 2010 to 2020. Infants who died within the first 10 days of life were excluded. MWL in the first 10 days was the main exposure, categorized into three groups: >15%, 5-15%, and < 5%. The primary outcome evaluated was the occurrence of death or neurodevelopmental impairment (NDI) at age 3 years, defined as developmental impairments (deve

SUBMITTER: Tamai K 

PROVIDER: S-EPMC11440999 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature