Assessing vaccine strategies for mpox outbreak in New York City using an age-structure model.

ABSTRACT:

Background

Since May 7 2022, mpox has been endemic in many countries which has attracted the attention of health authorities in various countries and made control decisions, in which vaccination is the mainstream strategy. However, the shortage of vaccine doses and the reduction of protective efficacy have led to unresolved issues such as vaccine allocation decisions and evaluation of transmission scale.

Methods

We developed an epidemiological model to describe the prevalence of the mpox virus in New York City and calibrated the model to match surveillance data from May 19 to November 3, 2022. Finally, we adjusted the model to simulate and compare several scenarios of non-vaccination and pre-pandemic vaccination.

Results

Relative to the status quo, if vaccination is n

SUBMITTER: Xiong Z 

PROVIDER: S-EPMC11441002 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature