Microbial community interactions on a chip.

ABSTRACT: Multispecies microbial communities drive most ecosystems on Earth. Chemical and biological interactions within these communities can affect the survival of individual members and the entire community. However, the prohibitively high number of possible interactions within a microbial community has made the characterization of factors that influence community development challenging. Here, we report a Microbial Community Interaction (µCI) device to advance the systematic study of chemical and biological interactions within a microbial community. The µCI creates a combinatorial landscape made up of an array of triangular wells interconnected with circular wells, which each contains either a different chemical or microbial strain, generating chemical gradients and revealing biological interact

SUBMITTER: Juang DS 

PROVIDER: S-EPMC11441501 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature