Functional network modules overlap and are linked to interindividual connectome differences during human brain development.

ABSTRACT: The modular structure of functional connectomes in the human brain undergoes substantial reorganization during development. However, previous studies have implicitly assumed that each region participates in one single module, ignoring the potential spatial overlap between modules. How the overlapping functional modules develop and whether this development is related to gray and white matter features remain unknown. Using longitudinal multimodal structural, functional, and diffusion MRI data from 305 children (aged 6 to 14 years), we investigated the maturation of overlapping modules of functional networks and further revealed their structural associations. An edge-centric network model was used to identify the overlapping modules, and the nodal overlap in module affiliations was quantified

SUBMITTER: Lei T 

PROVIDER: S-EPMC11441662 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature