The phytopathogen <i>Xanthomonas campestris</i> senses and effluxes salicylic acid via a sensor HepR and an RND family efflux pump to promote virulence in host plants.

ABSTRACT: Salicylic acid (SA) plays an essential role in plant defense against biotrophic and semi-biotrophic pathogens. Following pathogen recognition, SA biosynthesis dramatically increases at the infection site of the host plant. The manner in which pathogens sense and tolerate the onslaught of SA stress to survive in the plant following infection remains to be understood. The objective of this work was to determine how the model phytopathogen Xanthomonas campestris pv. campestris (Xcc) senses and effluxes SA during infection inside host plants. First, RNA-Seq analysis identified an SA-responsive operon Xcc4167-Xcc4171, encoding a MarR family transcription factor HepR and an RND (resistance-nodulation-cell division) family efflux pump HepABCD in Xcc. Electrophoretic mobility shift a

SUBMITTER: Song K 

PROVIDER: S-EPMC11442134 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature