Herbal medicines for SOD1^G93A mice of amyotrophic lateral sclerosis: preclinical evidence and possible immunologic mechanism.

ABSTRACT: Currently, there is no cure or effective treatment for Amyotrophic Lateral Sclerosis (ALS). The mechanisms underlying ALS remain unclear, with immunological factors potentially playing a significant role. Adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA), a systematic review of preclinical studies was conducted, searching seven databases including PubMed, covering literature from the inception of the databases to April 10, 2024. Methodological quality of the included literature was assessed using CAMARADES, while the risk of bias in the included studies was evaluated using SYRCLE's ROB tool. Review Manager 5.4.1 statistical software was used for meta-analysis of the outcomes. The scoping review followed the Joanna Briggs Institute Methodological Gu

SUBMITTER: Yang JL 

PROVIDER: S-EPMC11442286 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature