The location of cationic substitutions in carbonated biomimetic apatites significantly affects crystal nanomechanics.

ABSTRACT: Bone and teeth are comprised of carbonate-substituted apatites with cationic substitutions, like sodium and potassium. Cations substitute for calcium in the apatite lattice but it is unclear whether they substitute for Ca(1) or Ca(2). Additionally, although we know that anionic substitutions affect the mineral mechanics, it is unclear how cationic substitutions affect mineral stiffness. Here, a combined experimental and theoretical approach using in situ fluid-mediated hydrostatic loading with synchrotron Wide Angle X-ray Scattering (WAXS) and Density Functional Theory (DFT) is used to elucidate the role of CO₃^2- and Na⁺ or K⁺ co-substitutions on the atomic structure and mechanics of biomimetic apatites. Comparison of WAXS and DFT results showed

SUBMITTER: Wong S 

PROVIDER: S-EPMC11442586 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature