Effect of Statins for Primary Prevention of Cardiovascular Disease According to the Fatty Liver Index.

ABSTRACT:

Introduction

Nonalcoholic fatty liver disease (NAFLD) is associated with increased risk of cardiovascular disease (CVD). We investigated the primary preventive effect of statins on CVD according to the level of fatty liver index (FLI), which is a marker of NAFLD.

Methods

We conducted a nested case-control study on the basis of a nationwide health screening cohort in Korea. The participants were divided into tertiles (T1, T2, and T3) according to their FLI score. Cases were defined as individuals who developed CVD (composite of myocardial infarction and stroke). Three controls were matched to each case and multivariable conditional logistic regression analysis was performed.

Results

Within a cohort of 206,263 participants without prior CVD, 7044 individuals suffered th

SUBMITTER: Yoo J 

PROVIDER: S-EPMC11442725 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature