Patient-reported outcome measures for lupus nephritis: content validity of LupusQoL and FACIT-Fatigue.

ABSTRACT:

Background

Lupus nephritis (LN), a severe organ manifestation of systemic lupus erythematosus (SLE), significantly impacts health-related quality of life (HRQoL). Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue) and Lupus Quality of Life (LupusQoL) have been validated to measure HRQoL in SLE, but not specifically in LN. Patient-reported symptoms of LN are not well-reported. We assessed the content validity and relevance of these measures in evaluating patients with LN and their LN-related experiences.

Methods

This qualitative, interview-based study enrolled patients with LN from three US sites from a larger, retrospective survey study. The interview comprised an open-ended concept elicitation part and a more structured cognitive part. Concept elicitat

SUBMITTER: Martin ML 

PROVIDER: S-EPMC11442872 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature