Evaluation of Changes in Social Isolation and Loneliness with Incident Cardiovascular Events and Mortality.

ABSTRACT:

Background

It remains unknown how the patterns of change of social isolation and loneliness are associated with the onset of cardiovascular disease (CVD) and mortality. We aimed to investigate the longitudinal association of changes in social isolation and loneliness with incident CVD, all-cause mortality, CVD mortality and subsequent cardiac function.

Methods

This prospective cohort study included 18,258 participants aged 38-73 years who participated in visit 0 (2006-2010) and visit 1 (2012-2013) using UK Biobank (mean age 57.1, standard deviation [SD] 7.4; 48.7% males). Social isolation or loneliness was categorized into four patterns: never, transient, incident, and persistent. Incident CVD, all-cause and CVD mortality were ascertained through linkage data. Cardiac functi

SUBMITTER: Chen Y 

PROVIDER: S-EPMC11442883 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature