Factors associated with physical function among people with systemic sclerosis: a SPIN cohort cross-sectional study.

ABSTRACT:

Objectives

To compare physical function in systemic sclerosis (SSc, scleroderma) to general population normative data and identify associated factors.

Methods

Scleroderma Patient-centered Intervention Network Cohort participants completed the Physical Function domain of the Patient-Reported Outcomes Measurement Information System Version 2 upon enrolment. Multivariable linear regression was used to assess associations of sociodemographic, lifestyle, and disease-related variables.

Results

Among 2385 participants, the mean physical function T-score (43.7, SD = 8.9) was ∼2/3 of a standard deviation (SD) below the US general population (mean = 50, SD = 10). Factors associated in the multivariable analysis included older age (-0.74 points per SD years, 95% CI -0.78 to -1.0

SUBMITTER: Dal Santo T 

PROVIDER: S-EPMC11443018 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature