Evaluating the efficacy of uniformly designed square mesh resin 3D printed scaffolds in directing the orientation of electrospun PCL nanofibers.

ABSTRACT: Replicating the architecture of extracellular matrices (ECM) is crucial in tissue engineering to support tissues' natural structure and functionality. The ECM's structure plays a significant role in directing cell alignment. Electrospinning is an effective technique for fabricating nanofibrous substrates that mimic the architecture of extracellular matrices (ECM). This study aims to evaluate the efficacy of resin 3D-printed scaffolds made from a low-conductivity material (i.e., a resin composed of methacrylated oligomers, monomers, and photoinitiators) in directing the alignment of electrospun polycaprolactone (PCL) nanofibers. Six 3D-printed scaffolds were fabricated using stereolithography (SLA) technology and strategically positioned on an aluminum foil collector plate during electrospi

SUBMITTER: Fair E 

PROVIDER: S-EPMC11443100 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature