Absolute coronary flow and microvascular resistance before and after transcatheter aortic valve implantation.

ABSTRACT:

Background

Severe aortic stenosis (AS) is associated with left ventricular (LV) remodelling, likely causing alterations in coronary blood flow and microvascular resistance.

Aims

We aimed to evaluate changes in absolute coronary flow and microvascular resistance in patients with AS undergoing transcatheter aortic valve implantation (TAVI).

Methods

Consecutive patients with AS undergoing TAVI with non-obstructive coronary artery disease in the left anterior descending artery (LAD) were included. Absolute coronary flow (Q) and microvascular resistance (R_μ) were measured in the LAD using continuous intracoronary thermodilution at rest and during hyperaemia before and after TAVI, and at 6-month follow-up. Total myocardial mass and LAD-specific mass were quantifi

SUBMITTER: Gallinoro E 

PROVIDER: S-EPMC11443252 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature