Changes in Cognitive Function After Kidney Transplantation: A Longitudinal Cohort Study.

ABSTRACT:

Rationale & objective

Kidney disease negatively affects cognition. We assessed the effect of kidney transplantation (KT) on different cognitive domains.

Study design

Prospective cohort study.

Setting & participants

We examined pre- versus post-KT cognition in patients waitlisted for KT at an academic center.

Predictors

Transplant status. We measured cognitive function before KT (n=101), 3 months after KT (n=78), and 1 year after KT (n = 83).

Outcomes

Our primary outcome was change in cognitive function before versus after KT. We used standard neuropsychological tests to assess global cognition (Mini-Mental State Exam [MMSE]), episodic/declarative memory (Logical Memory), psychomotor speed/visuospatial function (Digit Symbol Substitution Test [DSST], Trai

SUBMITTER: Gupta A 

PROVIDER: S-EPMC11443557 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature