Dissemination and outcome reporting bias in clinical malaria intervention trials: a cross-sectional analysis.

ABSTRACT:

Background

Dissemination and outcome reporting biases are a significant problem in clinical research, with far-reaching implications for both scientific understanding and clinical decision-making. This study investigates the prevalence of dissemination- and outcome reporting biases in registered interventional malaria research.

Methods

All malaria interventional trials registered on ClinicalTrials.gov from 2010 to 2020 were identified. Subsequently, publications that matched the registration were searched. The primary outcome measures were the percentage of registered studies that resulted in subsequent publication of study results, the concordance between registered outcomes, and reported outcomes. Secondary outcomes were compliance with WHO standards for timely publication

SUBMITTER: Pool L 

PROVIDER: S-EPMC11443699 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature