Correlation between triglyceride-glucose index and diabetic kidney disease risk in adults with type 1 diabetes mellitus.

ABSTRACT:

Background

The triglyceride-glucose (TyG) index is identified as an alternative indicator of insulin resistance (IR) and is associated with macro- and micro-vascular diseases among patients with type 2 diabetes mellitus. The relationship between the TyG index and IR and its impact on diabetic kidney disease (DKD) remains unclear among adults with type 1 diabetes mellitus(T1DM).

Methods

This study comprised a cross-sectional analysis using data from the Guangdong T1DM Translational Medicine Study (GTT) and a longitudinal analysis using data from the type 1 diabetes (T1D) Exchange registry study. Correlation analysis was used to investigate the association between the TyG index and IR. Logistic regression and Cox proportional hazards regression were performed to explore the im

SUBMITTER: Lei M 

PROVIDER: S-EPMC11443788 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature