Prenatal Exposure to Nonpersistent Chemicals and Fetal-to-childhood Growth Trajectories.

ABSTRACT:

Introduction

Prenatal exposure to nonpersistent chemicals, including organophosphate pesticides, phthalates, and bisphenols, is associated with altered fetal and childhood growth. Few studies have examined these associations using longitudinal growth trajectories or considering exposure to chemical mixtures.

Methods

Among 777 participants from the Generation R Study, we used growth mixture models to identify weight and body mass index trajectories using weight and height measures collected from the prenatal period to age 13. We measured exposure biomarkers for organophosphate pesticides, phthalates, and bisphenols in maternal urine at three timepoints during pregnancy. Multinomial logistic regression was used to estimate associations between averaged exposure biomarker conce

SUBMITTER: Bommarito PA 

PROVIDER: S-EPMC11444368 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature