Clinical presentation of human leptospirosis in febrile patients: Uraba, Colombia.

ABSTRACT:

Background

Leptospirosis is responsible for various clinical syndromes, classically linked with fever and acute kidney injury.

Methodology/principal findings

A prospective multicenter observational study was conducted in six health institutions in the region of Urabá, Colombia. Enrollment was based on leptospirosis-compatible clinical syndrome and a positive preliminary serological test, with PCR used to confirm the disease. Clinical data were collected using a standard questionnaire at enrollment, complemented with a review of clinical records. A total of 100 patients were enrolled, 37% (95% CI 27.0-46.9%) had a positive PCR result confirming acute leptospirosis. The most frequent symptoms in patients with a positive PCR test were headache (91.9%; 34/37), chills and sweatin

SUBMITTER: Uribe-Restrepo P 

PROVIDER: S-EPMC11444379 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature