A Retrospective Study of the Histopathological Spectrum of Erythema Nodosum Leprosum.

ABSTRACT:

Background

There are no recent studies with a focus on the histopathology of erythema nodosum leprosum (ENL).

Objectives

To describe the histopathological spectrum of ENL.

Materials and methods

Digital records from the pathology department were searched, and 125 slides were included. The histopathologic findings were recorded using a pre-designed proforma.

Results

Several patterns were noted with the most common being a superficial and deep, perivascular and peri-appendageal, well-circumscribed dermal infiltrate that was seen in 70 (56.0%) biopsies. Other dermal patterns included a similar but loose infiltrate in 19 (15.2%) biopsies, diffuse dermal involvement in 9 (7.2%), top-heavy in 9 (7.2%), and bottom-heavy infiltrates in 12 (9.6%). Subcutaneous tissue was

SUBMITTER: Patel V 

PROVIDER: S-EPMC11444462 | biostudies-literature | 2024 Sep-Oct

REPOSITORIES: biostudies-literature