Familial genetic and environmental transmission of depression: A multi-informant twin family study.

ABSTRACT: The phenomenon of familial clustering in depression is well established, yet the mechanisms by which depression is transmitted within families remain poorly understood. In the current study, we investigate the familial genetic and environmental transmission of depression by incorporating data from both adolescent twins and their parents. A total of 987 twin families were recruited from the Beijing Twin Study. Depression assessments were conducted for both adolescents and their parents. Twins' depression was assessed through reports from both the twins themselves and their parents, while parental depression was assessed by parental self-report. We employed a nuclear twin family model to examine genetic and environmental influences on adolescent depression. Our results, based on both self- a

SUBMITTER: Ding Q 

PROVIDER: S-EPMC11444726 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature