Effects of food containing <i>Lactococcus lactis</i> strain T21 on the improvement of skin condition: a randomized, double-blind, placebo-controlled, parallel-group study.

ABSTRACT: This research aimed to examine the effect of daily intake of food containing Lactococcus lactis strain T21 (T21) on skin conditions and inflammation-related markers in healthy adults who experience itching because of dry skin and have an atopic predisposition. A randomized, double-blind, placebo-controlled parallel-group study was conducted on 44 subjects aged 20 to 64 years. Subjects were randomly assigned to receive a T21-containing food or placebo daily for 8 weeks. The hydration of stratum corneum, trans-epidermal water loss, skin brightness (L*), skin redness (a*), and quality of life (QOL) scores were evaluated. Moreover, SCCA2, Th1/Th2, peripheral blood eosinophil count, TGF-β1, TARC, total IgE, and LDH were measured as inflammation-related markers. The results

SUBMITTER: Uehara K 

PROVIDER: S-EPMC11444856 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature