Bladder cancer incidence and mortality among men with and without castration therapy for prostate cancer - a nation-wide cohort study.

ABSTRACT:

Background and purpose

Bladder cancer (BC) is a common malignancy in the Western World with men being diagnosed almost four times as often as women. The etiology of bladder cancer may involve sex hormones. Prostate cancer (PCa) patients treated with chemical castration, such as androgen deprivation therapy, or surgical castration, may therefore have a lower risk of developing bladder cancer.

Patients/material and methods

In a nation-wide population-based cohort study using national Danish registry data, we included a cohort of men with a first-time PCa diagnosis between 2002 and 2018 divided according to antihormonal treatment in the first year after PCa diagnosis and a comparison cohort consisting of 10 age-matched persons for each PCa patient. Each individual was followed

SUBMITTER: Hyldgaard JM 

PROVIDER: S-EPMC11445587 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature