The efficacy of orally administered L-carnitine in alleviating ovarian dysfunctions has laid the foundation for targeted <i>in vivo</i> use: a study employing self-control and propensity score matching.

ABSTRACT:

Objective

This study aimed to evaluate the effectiveness of oral L-carnitine administration in patients after treatment failure to lay the groundwork for targeted in vivo use.

Methods and materials

A total of 515 In Vitro Fertilization (IVF) patients undergoing subsequent cycles were included after applying exclusion criteria. They were divided into a control group of 362 patients and a study group of 153 patients who received oral L-carnitine until oocyte retrieval.140 patients were matched according to maternal age, infertility duration, body mass index (BMI), day three top-quality embryos rate, by propensity score matching (PSM). The study investigated the relationship between L-carnitine treatment and in vivo oocyte maturation, normal fertilization,

SUBMITTER: Zhao W 

PROVIDER: S-EPMC11445680 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature