Short-term (24 weeks) treatment efficacy and safety of ruxolitinib cream in participants with vitiligo: a systematic review and meta-analysis.

ABSTRACT:

Importance

Vitiligo is a chronic skin disorder causing depigmentation. There is a lack of evidence-based medical evidence regarding ruxolitinib efficacy and safety for vitiligo.

Objective

To assess the efficacy and safety of ruxolitinib cream in the treatment of vitiligo.

Methods

The databases of PubMed, Embase, and Cochrane Library were searched. The literature screening was independently conducted by two reviewers.

Data extraction and synthesis

For continuous variables, weighted mean difference (WMD) along with a 95% confidence interval (CI) was performed. For dichotomous outcomes, we calculated the odds ratios (ORs) or risk ratios (RRs), and their corresponding 95% CIs. The certainty of evidence was evaluated using the Grading of Recommendations, Assessment,

SUBMITTER: Yuan Y 

PROVIDER: S-EPMC11445846 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature