Neuroanatomical profiles of cognitive phenotypes in patients with primary brain tumors.

ABSTRACT:

Background

Patients with brain tumors demonstrate heterogeneous patterns of cognitive impairment, likely related to multifactorial etiologies and variable tumor-specific factors. Cognitive phenotyping offers a patient-centered approach to parsing heterogeneity by classifying individuals based on patterns of impairment. The aim of this study was to investigate the neuroanatomical patterns associated with each phenotype to gain a better understanding of the mechanisms underlying impairments.

Methods

Patients with primary brain tumors were recruited for a prospective, observational study. Patients were cognitively phenotyped using latent profile analysis in a prior study, revealing 3 distinct groups: generalized, isolated verbal memory, and minimal impairment</

SUBMITTER: Kohli JS 

PROVIDER: S-EPMC11445899 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature