A comparison of measurement properties between EORTC QLU-C10D and FACT-8D in patients with hematological malignances.

ABSTRACT:

Objective

To perform a comparison of the measurement properties of two cancer-specific Multi-Attribute Utility Instruments (MAUIs), EORTC QLU-C10D and FACT-8D, in Chinese patients with hematologic malignancies (HM).

Methods

We conducted a longitudinal study on patients with HM in China, using QLU-C10D and FACT-8D at baseline and follow-up (3-4 months from baseline). We assessed: (i) convergent validity using Spearman's rank correlation test (r) with EQ-5D-5L; (ii) clinical-groups validity by differentiating cancer stages, overall health assessment (OHA), Eastern Cancer Oncology Group (ECOG) performance status, and mental health status. We also examined clinical validity with effect size (ES) and relative efficiency (RE); (iii) responsiveness to changes in patient self-percep

SUBMITTER: Cao Y 

PROVIDER: S-EPMC11445936 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature