Beyond the biting - limited impact of explicit mosquito dynamics in dengue models.

ABSTRACT: Mathematical models play a crucial role in assisting public health authorities in timely disease control decision-making. For vector-borne diseases, integrating host and vector dynamics into models can be highly complex, particularly due to limited data availability, making system validation challenging. In this study, two compartmental models akin to the SIR type were developed to characterize vector-borne infectious disease dynamics. Motivated by dengue fever epidemiology, the models varied in their treatment of vector dynamics, one with implicit vector dynamics and the other explicitly modeling mosquito-host contact. Both considered temporary immunity after primary infection and disease enhancement in secondary infection, analogous to the temporary cross-immunity and the Antibody-depend

SUBMITTER: Steindorf V 

PROVIDER: S-EPMC11446025 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature