The impact of cannabis use proximal to sleep and cannabinoid metabolites on sleep architecture.

ABSTRACT:

Study objectives

Cannabis is a common sleep aid; however, the effects of its use prior to sleep are poorly understood. This study aims to determine the impact of nonmedical whole plant cannabis use 3 hours prior to sleep and measured cannabis metabolites on polysomnogram measures.

Methods

This is a cross-sectional study of 177 healthy adults who provided detailed cannabis use history, underwent a 1-night home sleep test and had measurement of 11 plasma and urinary cannabinoids, quantified using mass spectroscopy, the morning after the home sleep test. Multivariable models were used to assess the relationship between cannabis use proximal to sleep, which was defined as use 3 hours before sleep, and individual home sleep test measurements. Correlation between metabolite concen

SUBMITTER: Althoff MD 

PROVIDER: S-EPMC11446118 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature