Narcolepsy and risk of traumatic injury: a population-based matched cohort study.

ABSTRACT:

Study objectives

We evaluated the risk of traumatic injury in patients with narcolepsy compared to the general population.

Methods

We conducted a population-based matched cohort study using a Japanese health insurance claims database. For each patient with narcolepsy, up to 5 individuals from the general population without narcolepsy were matched by variables such as sex, age, and cohort entry month. The primary outcome was traumatic injury, and the secondary outcome was fracture. The study population was followed for up to 5 years from the cohort entry date. We estimated crude incidence rates, adjusted incidence rate differences, adjusted hazard ratios, and their 95% confidence intervals (CIs) for study outcomes using crude and multivariable Poisson and Cox regression model

SUBMITTER: Zheng Y 

PROVIDER: S-EPMC11446133 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature