Bronchodilator Response in Post-COVID-19 Patients Undergoing Pulmonary Rehabilitation.

ABSTRACT:

Introduction

SARS-CoV-2 infections can result in a broad spectrum of symptoms from mild to life-threatening. Long-term consequences on lung function are not well understood yet.

Methods

In our study, we have examined 134 post-COVID patients (aged 54.83 ± 14.4 years) with dyspnea on exertion as a leading symptom 6 weeks to 24 months after a SARS-CoV-2 infection for bronchodilator responsiveness during their stay in our pulmonary rehabilitation clinic.

Results

Prior to bronchial dilation, 6 out of 134 patients (4.47%) presented an FEV1/FVC ratio below lower limit of normal (Z-score = -1.645) indicative of an obstructive airway disease. Following inhalation of a β2-adrenergic agonist we measured a mean FEV1 increase of 181.5 mL in our cohort, which was significantly elev

SUBMITTER: Krooss SA 

PROVIDER: S-EPMC11446304 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature