Performance of a Diagnostic Model for the Presence of Unruptured Intracranial Aneurysms in the General Population.

ABSTRACT:

Introduction

The prevalence of unruptured intracranial aneurysms (UIAs) in the general population is 3%. Aneurysmal subarachnoid hemorrhage can be prevented by screening for UIAs followed by monitoring and, if needed, preventive neurosurgical or endovascular treatment of identified UIAs. Therefore, we developed a diagnostic model for the presence of UIAs in the general population to help identify persons at high risk of having UIAs.

Methods

Between 2005 and 2015, participants from the population-based Rotterdam Study underwent brain magnetic resonance imaging at 1.5 T, on which the presence of incidental UIAs was evaluated. We developed a multivariable logistic regression model using candidate diagnostic markers that were selected based on the literature, including sex, age,

SUBMITTER: Klieverik VM 

PROVIDER: S-EPMC11446332 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature