Prevalence and predictors of mitral annular disjunction and ventricular ectopy in mitral valve prolapse.

ABSTRACT:

Background

Mitral annular disjunction (MAD) is associated with ventricular arrhythmia in mitral valve prolapse (MVP). The proportional risk from MAD and other predictors of ventricular arrhythmia in MVP has not been well characterized.

Objective

This study aimed to identify predictors of complex or frequent ventricular ectopy (cfVE) in MVP and to quantify risk of cfVE and mortality in MVP with MAD.

Methods

We studied 632 adult patients with MVP on transthoracic echocardiography at the University of North Carolina Medical Center from 2016 to 2019 (median age, 64 [interquartile range, 52-74] years; 52.7% female; 16.3% African American). Resting and ambulatory electrocardiograms were used to identify cfVE.

Results

MAD was present in 94 (14.9%) patients. Independen

SUBMITTER: Cesmat AP 

PROVIDER: S-EPMC11446644 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature