Co-morbid sarcopenia and low bone mineral density in young paediatric cancer survivors.

ABSTRACT:

Background

Sarcopenia and low areal bone mineral density (aBMD) are prevalent musculoskeletal complications after paediatric cancer treatment. However, their relationship has not been examined in young paediatric cancers survivors. This study aimed to evaluate aBMD differences according to sarcopenia status and the risk of low aBMD Z-score in young paediatric cancer survivors with sarcopenia confirmed/probable.

Methods

This cross-sectional study included 116 paediatric cancer survivors (12.1 ± 3.3 years old; 42.2% female). Handgrip strength was used to assessed muscle strength. Dual-energy X-ray absorptiometry estimated aBMD (g/cm²) and appendicular lean mass index (ALMI, kg/m²). 'No sarcopenia' was defined when muscle strength was >decile 2. 'Sarcopeni

SUBMITTER: Marmol-Perez A 

PROVIDER: S-EPMC11446677 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature