Network statistics of the whole-brain connectome of Drosophila.

ABSTRACT: Brains comprise complex networks of neurons and connections, similar to the nodes and edges of artificial networks. Network analysis applied to the wiring diagrams of brains can offer insights into how they support computations and regulate the flow of information underlying perception and behaviour. The completion of the first whole-brain connectome of an adult fly, containing over 130,000 neurons and millions of synaptic connections^1-3, offers an opportunity to analyse the statistical properties and topological features of a complete brain. Here we computed the prevalence of two- and three-node motifs, examined their strengths, related this information to both neurotransmitter composition and cell type annotations^4,5, and compared these metrics with wiring diagrams

SUBMITTER: Lin A 

PROVIDER: S-EPMC11446825 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature