Optical coherence tomography measurements in Huntington's disease: a systematic review and meta-analysis.

ABSTRACT:

Background

A connection has been established between ocular structural changes and various neurodegenerative diseases. Several studies utilizing optical coherence tomography (OCT) have detected signs of ocular structural alterations among individuals with Huntington's disease (HD). The inconsistent results reported in the literature regarding alterations in the retina and choroid encouraged us to conduct this systematic review and meta-analysis to accumulate the findings.

Methods

A systematic search was carried out in three electronic databases (PubMed, Embase, Scopus) to find studies reporting OCT measurements in HD cases compared with healthy controls (HC). A fixed-effects or random-effects meta-analysis was conducted according to the detected heterogeneity level. Furtherm

SUBMITTER: Gouravani M 

PROVIDER: S-EPMC11447008 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature