Association between autoimmunity-related disorders and prostate cancer: A Mendelian randomization study.

ABSTRACT:

Background

Although many epidemiological studies and meta-analyses have reported an association between autoimmune disorders and prostate cancer, none has reported a clear correlation or the direction of the association. The purpose of our study was to explore the potential relationship between autoimmunity-related disorders and prostate cancer using Mendelian randomization (MR).

Methods

We retrieved literature from PubMed using the keywords "autoimmune disorder" AND "prostate cancer" to find more clues on the correlation between prostate cancer and autoimmunity-related disorder. Based on this literature search, we selected 16 autoimmunity-related disorders that had genome-wide association study (GWAS) data and may be associated with prostate cancer. The inverse variance wei

SUBMITTER: Chen P 

PROVIDER: S-EPMC11447306 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature