Alternative splicing dynamically regulates common carp embryogenesis under thermal stress.

ABSTRACT:

Background

Thermal stress is a major environmental factor affecting fish development and survival. Common carp (Cyprinus carpio) are susceptible to heat stress in their embryonic and larval phases, but the thermal stress response of alternative splicing during common carp embryogenesis remains poorly understood.

Results

Using RNA-seq data from eight developmental stages and four temperatures, we constructed a comprehensive profile of alternative splicing (AS) during the embryogenesis of common carp, and found that AS genes and events are widely distributed among all stages. A total of 5,835 developmental stage-specific AS (SAS) genes, 21,368 temperature-specific differentially expressed genes (TDEGs), and 2,652 temperature-specific differentially AS (TDAS) genes were identif

SUBMITTER: Hu S 

PROVIDER: S-EPMC11448050 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature