The joint effect of cumulative metabolic parameters on the risk of type 2 diabetes: a population-based cohort study.

ABSTRACT:

Background and aims

This study aimed to examine the cumulative effects of body mass index (BMI), body roundness index (BRI), pulse pressure (PP), triglycerides (TG), high-density lipoprotein cholesterol (HDL) and fasting plasma glucose (FPG) on Type 2 diabetes (T2D) morbidity.

Methods

A total of 78,456 participants aged older than 45 years were extracted from basic public health services in China. During the 2-year follow-up, 6,942 individuals had developed T2D. The binary logistic regression models and multinomial logistic regression models were conducted to investigate the effects of cumulative metabolic parameters on incident T2D, prediabetes regression and progression.

Results

We found statistically deleterious impacts of exposure to high cumulative BMI, BRI, PP,

SUBMITTER: Xiong WY 

PROVIDER: S-EPMC11448077 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature