Changes in colloid oncotic pressure during cardiac surgery with different prime fluid strategies.

ABSTRACT:

Objective

In cardiac surgery, colloid oncotic pressure (COP) is affected by haemodilution that results from composition and volume of prime fluid of cardiopulmonary bypass (CPB). However, the extent to which different priming strategies alter COP is largely unknown. Therefore, we investigated the effect of different priming strategies on COP in on-pump cardiac surgery.

Methods

Patients (n = 60) were divided into 3 groups (n = 20 each), based on the center in which they were operated and the specific prime fluid strategy used in that center during the inclusion period. CPB prime fluids were either gelofusine-, albumin-, or crystalloid based, the latter two with or without retrograde autologous priming.

Results

In all groups, COP was lowest after weaning f

SUBMITTER: Beukers AM 

PROVIDER: S-EPMC11448106 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature