Microbial interactions impact stress tolerance in a model oral community.

ABSTRACT: Understanding the molecular mechanisms governing microbial interactions is crucial for unraveling the complexities of microbial communities and their ecological impacts. Here, we employed a two-species model system comprising the oral bacteria Aggregatibacter actinomycetemcomitans and Streptococcus gordonii to investigate how synergistic and antagonistic interactions between microbes impact their resilience to environmental change and invasion by other microbes. We used an in vitro colony biofilm model and focused on two S. gordonii-produced extracellular molecules, L-lactate and H₂O₂, which are known to impact fitness of this dual-species community. While the ability of A. actinomycetemcomitans to cross-feed on S. gordonii

SUBMITTER: Lewin GR 

PROVIDER: S-EPMC11448157 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature