RESIST ACINETO test for the rapid detection of NDM and OXA acquired carbapenemases directly from blood culture in <i>Acinetobacter</i> species.

ABSTRACT: Carbapenem-resistant Acinetobacter baumannii (CRAB) are increasingly reported worldwide and a leading cause of mortality associated with antimicrobial resistance. Their early detection, particularly in the cases of bloodstream infections, is crucial in attempting to initiate effective antibiotic treatment. The immunochromatographic assay RESIST ACINETO (Coris BioConcept) is a new test developed for the detection of OXA-23, OXA-40/58, and New-Delhi Metallo-beta-lactamase (NDM) carbapenemases in Acinetobacter spp. We evaluated this test on a collection of 121 Acinetobacter spp. clinical isolates, including 104 carbapenemase producers (97 carbapenemases targeted by the test) and 17 non-carbapenemase producers. The performance of the RESIST ACINETO test was evaluated accor

SUBMITTER: Potron A 

PROVIDER: S-EPMC11448386 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature