Microbiome time series data reveal predictable patterns of change.

ABSTRACT: The human gut microbiome is crucial in health and disease. Longitudinal studies are becoming increasingly important compared to traditional cross-sectional approaches, as precision medicine and individualized interventions are coming to the forefront. Investigating the temporal dynamics of the microbiome is essential for comprehending its function and impact on health. This knowledge has implications for targeted therapeutic strategies, such as personalized diets or probiotic therapy. In this study, we focused on developing and implementing methods specifically designed for analyzing gut microbiome time series. Our statistical framework provides researchers with tools to examine the temporal behavior of the gut microbiome. Key features of our framework include statistical tests for time se

SUBMITTER: Karwowska Z 

PROVIDER: S-EPMC11448390 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature