Clinical and pathogen features of COVID-19-associated infections during an Omicron strain outbreak in Guangzhou, China.

ABSTRACT: Although the Omicron variant has been associated with greater transmissibility and tropism of the upper respiratory tract, the clinical and pathogenic features of patients infected with the Omicron variant during an outbreak in China have been unclear. Adults with COVID-19 were retrospectively enrolled from seven medical centers in Guangzhou, China, and clinical information and specimens ( BALF, sputum, and throat swabs) from participants were collected. Conventional detection methods, metagenomics next-generation sequencing (mNGS), and other methods were used to detect pathogens in lower respiratory tract samples. From December 2022 to January 2023, we enrolled 836 patients with COVID-19, among which 56.7% patients had severe/critical illness. About 91.4% of patients were infected with th

SUBMITTER: Cheng L-l 

PROVIDER: S-EPMC11448415 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature