Burden of tuberculosis in underserved populations in South Africa: A systematic review and meta-analysis.

ABSTRACT: Identifying case-finding strategies to reduce tuberculosis (TB) incidence in high-burden countries requires better knowledge of the disease burden in key contributing populations and settings. To inform South Africa's National Tuberculosis Strategic Plan 2023-2028, we conducted a systematic review of active TB disease and latent TB infection (LTBI) prevalence and incidence in underserved populations, defined as those living in informal settlements, townships, or impoverished communities. We identified articles published from January 2010 to December 2023, assessed study quality, and conducted a meta-analysis to estimate pooled TB and LTBI prevalence stratified by HIV status. We calculated prevalence ratios for underserved populations compared to the overall South African population. The se

SUBMITTER: Holtgrewe LML 

PROVIDER: S-EPMC11449336 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature