Risk factors for COVID-19 transmission in England: a multilevel modelling study using routine contact tracing data.

ABSTRACT: Contact tracing for COVID-19 in England operated from May 2020 to February 2022. The clinical, demographic and exposure information collected on cases and their contacts offered a unique opportunity to study secondary transmission. We aimed to quantify the relative impact of host factors and exposure settings on secondary COVID-19 transmission risk using 550,000 sampled transmission links between cases and their contacts. Links, or 'contact episodes', were established where a contact subsequently became a case, using an algorithm accounting for incubation period, setting, and contact date. A mixed-effects logistic regression model was used to estimate adjusted odds of transmission. Of sampled episodes, 8.7% resulted in secondary cases. Living with a case (71% episodes) was the most signifi

SUBMITTER: Moore HL 

PROVIDER: S-EPMC11450508 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature