An octahedral coordination cage with six Fe(III) centers as a T₁ MRI probe.

ABSTRACT: The incorporation of multiple Fe(III) centers bridged by rigid ligands into a coordination cage represents a powerful approach for designing effective MRI contrast agents. In this context, an octahedral coordination cage with six high-spin Fe(III) centers is shown to be water soluble, robust towards dissociation and has effective relaxivity as a T₁ MRI probe in solution and in mice.

SUBMITTER: Dissanayake A 

PROVIDER: S-EPMC11450543 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature